Kelly Science and Clinical is currently hiring a Principal Investigator to work part-time, onsite in Houston TX for one of our clients who is dedicated to advancing medical innovation and healing technology through groundbreaking research.

• Location: On-site in Houston TX  (some remote chart review/sponsor calls as studies permit)
• Hours: 5 - 15 hours/week depending on the study needs  
  • The exact hours will vary based on the needs of the clinical trial study, offering both adaptability and the opportunity to work on a dynamic and engaging project
• Pay: Depends on industry experience. Range of $120 - $150.00 / 1099 hourly 
• Duration: Long term, no end date with potential to grow with the team as well as add additional hours if warranted 

About the Role:
We’re seeking Family Medicine or Internal Medicine Physicians to serve as Principal Investigators (PIs) at our Houston, TX research site. This position is ideal for physicians seeking a slower pace of work and very flexible, part-time hours (approximately 5–15 hours/week depending on study needs). Comprehensive PI onboarding and ongoing support are provided. You’ll provide medical oversight for clinical trials, ensure participant safety, and help generate high-quality data—without the heavy demands of a traditional clinic schedule. We’re looking for amazing candidates with clinical trial experience, as well as a Schedule I or II license (preferred). 

Key Responsibilities:
•    Serve as the study physician for assigned trials; ensure participant safety and ethical conduct.
•    Review and confirm participant eligibility; oversee screening outcomes, AEs/SAEs, and retention trends.
•    Perform/oversees study-specific medical assessments (histories/physicals, concomitant meds, endpoint review).
•    Provide medical oversight to site staff (Sub-Investigators, CRCs, RNs, lab staff); be available for consults and safety questions.
•    Collaborate with IRBs, sponsors, and CROs; join SIVs, monitoring visits, and close-out activities as needed.
•    Ensure compliance with protocols, site SOPs, ICH-GCP, FDA/21 CFR, and Arizona or Texas state requirements (as applicable).
•    Review clinical data (labs, ECGs, vitals) and support timely safety reporting and documentation.
•    Contribute to high-quality source documentation, query resolution, and continuous improvement of site processes.

Minimum Qualifications:
•    MD or DO (Family or Internal Medicine).
•    Active, unrestricted TX Medical Board license, as applicable.
•    Experience in clinical research and comfort reviewing structured clinical data. Prior experience as a PI or Sub-Investigator is required. 
•    Strong documentation, communication, and confidentiality practices (HIPAA/PHI).
•    Familiarity with ICH-GCP and FDA regulations (21 CFR Parts 50, 54, 56, 312, 812).
•    Board certification in Family or Internal Medicine or relevant therapeutic area focus 

Preferred Qualifications:
•    DEA registration – Schedule I or II license, or are willing to obtain this license.