BeOne Medicines
CA
Aug 09, 2026
1 senior scientist epithelial and stromal biology san carlos california jobs found
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**General Description:**
**Candidates must be able to work onsite in San Carlos, California.**
At BeOne Institute, We Extend BeOne's Execution Strength With a Dedicated Innovation Engine, Bringing Agility And Scientific Depth To Transform Uncertainty Into Actionable And High-impact Therapeutic Opportunities. We Operate According To Three Core Principles:
+ Bold Exploration: we pursue novel and high-potential ideas through rapid, iterative innovation cycles.
+ Strategic Alignment: we prioritize disease areas that align closely with BeOne's R&D priorities and long-term vision.
+ Pipeline Impact: we translate insights into tangible assets and advance emerging platforms into impactful programs.
As a Senior Scientist at BeOne Institute, you will independently design and execute high-quality research studies supporting discovery and translational programs in immunology, inflammation, and immuno-oncology. You will contribute to target evaluation, mechanistic understanding, and therapeutic development through generation of rigorous, decision-enabling data.
**Essential Functions of the Job:**
+ Identify and advance high-value therapeutic targets across immunology, inflammation and immuno-oncology therapeutic areas, aligned with organizational strategy, portfolio priorities and emerging scientific opportunities.
+ Independently design, execute, analyze and interpret in vitro, ex vivo, and in vivo studies to validate target biology, establish disease rationale, evaluate therapeutic modalities, develop mechanistic insight, and generate decision-enabling data packages.
+ Communicate progress through regular updates while proactively identifying challenges and proposing solutions.
+ Collaborate with cross-disciplinary or cross-functional teams and drive innovation within and beyond the Institute.
+ Contribute to management and operational activities to support strategic objectives of the BeOne Institute at the San Carlos site.
**Supervisory Responsibilities:**
+ May mentor junior scientists, research associates, interns
**Requirements** **:**
+ **Requirements** **:** **Travel:** No
+ Ph.D., M.D., or equivalent advanced degree in one or more of the following areas : cancer biology, immuno-oncology, immunology, epithelial and stromal biology, stem cell biology or a related life sciences discipline. 2+ years of related experience.
+ Demonstrated track record of scientific achievements, as evidenced by publications in high-impact journals.
+ Demonstrated ability to design experiments, generate high-quality data, analyze complex datasets, and communicate scientific findings effectively.
+ Hands-on experience with relevant laboratory techniques such as primary human/mouse epithelial and stromal cell culture, air-lift culture, epithelial organoid culture, cell line engineering, histology, IHC, IF, flow cytometry, ELISA, MSD, molecular biology methods, protein characterization, microscopy/high-content imaging, or related experimental platforms.
+ Experience with one or more of the following is preferred: in vitro and in vivo disease models, AI-driven protein design, protein engineering, induced proximity technologies, synthetic biology approaches, or other innovative therapeutic platforms.
+ Knowledge of biologics, small molecules and other complex modalities, experience with omics data analysis, and/or preclinical immunology and oncology mouse models is a plus.
+ Ability to operate effectively in a highly collaborative, fast-paced, and interdisciplinary research environment, and to integrate multi-disciplinary approaches to solve complex biological problems.
+ Strong collaboration skills across functional and disciplinary boundaries.
+ Excellent communication and presentation skills, with the ability to clearly articulate complex scientific concepts to both technical and non-technical audiences.
**Education Required:**
Ph.D., M.D., or equivalent advanced degree
**Travel:** No
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
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