Job Description
Job Description
Job Description Summary:
Performs bench level experiments and small independent research projects to support scientific research objectives of a lab or group. Analyzes experimental data, addresses methodological problems in experimental protocols and results, and reports data to supervisor.
OVERVIEW
The Raguram Lab is seeking a highly motivated technical assistant to join our team. In the Raguram Lab, we investigate mechanisms of intercellular biomolecule transfer to inform the development of new methods for delivering macromolecular therapeutics into cells. Specifically, we study how viruses, vesicles, and other related cell-derived bioparticles become loaded with different molecular cargos and how these processes can be modulated to improve macromolecular delivery. The technical assistant will work closely with Dr. Aditya Raguram (principal investigator) and will be expected to perform a wide range of experiments to support the lab’s work, including molecular cloning, viral vector production and purification, CRISPR screens, and high-throughput sequencing. Additionally, the technical assistant will have the opportunity to lead independent research projects that could result in first-author publications. This is an ideal opportunity for recent graduates who are looking to gain additional research experience before attending graduate or medical school.
OVERALL RESPONSIBILITY
The Technical Assistant will participate in and eventually lead research projects to characterize and develop new macromolecular delivery methods. The Technical Assistant will design and execute experiments, analyze experimental data, address methodological problems in experimental protocols and results, and report data to the principal investigator.
CHARACTERISTIC DUTIES
- Conduct bench-level experiments and independent research projects under the mentorship of the Principal Investigator.
- Perform standard molecular biology experiments, e.g. PCR, plasmid preparation, RNA purification, molecular cloning.
- Perform mammalian cell tissue culture experiments, including the production and purification of viral vectors.
- Operate and maintain laboratory equipment to complete investigations.
- Prepare, order, and maintain stocks of necessary reagents, solutions, and supplies. May work with vendors to address equipment, reagent, or supply issues.
- Document, compile, and assist in interpreting experimental data. Report data to supervisor in oral and written reports.
- Consult scientific literature as needed.
- Other tasks as required or assigned.
QUALIFICATIONS
- Bachelor’s degree in biology, biochemistry, biological engineering or a related field.
- At least one year of undergraduate research experience.
- Proficiency in basic lab techniques and principles of molecular biology required.
- Excellent written and oral communication skills, strong organizational skills.
- Excellent collaborative and interpersonal skills.
- Prior experience with molecular cloning, tissue culture, and viral vectors preferred.
- Knowledge of various scientific databases and publications preferred.
Whitehead Institute is an E-Verify employer
https://e-verify.uscis.gov/web/media/resourcesContents/E-Verify_Participation_Poster_ES.pdf
Company Description
WHITEHEAD INSTITUTE for BIOMEDICAL RESEARCH
Whitehead Institute for Biomedical Research is a leading, nonprofit research and educational institution that has defined the cutting edge of biomedical science, creating a legacy of research excellence and academic eminence since 1982. Wholly independent in its governance, finances and research programs, Whitehead shares a teaching affiliation with Massachusetts Institute of Technology (MIT), offering the intellectual, collegial and scientific benefits of a leading research university. Whitehead’s Faculty Members and Fellows run pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics and genomics—programs with a record of success.
We offer excellent benefits including a choice of health insurance options; a generous retirement plan; comprehensive dental, disability and life insurance coverage; competitive salary, substantial vacation and holiday time; and programs for tuition reimbursement, dependent care assistance, pre-tax spending accounts, and subsidized public transportation or parking. We also offer relocation assistance.
The Whitehead Institute believes diversity, equity and inclusion (DE&I) are integral to its values and mission. As a research Institute dedicated to improving human health through biomedical science, we believe that diverse thought invokes creative inquiry, drives innovation, and fuels scientific breakthrough. We welcome all individuals of all backgrounds including race, ethnicity, gender identity and expression, sexual orientation, age, veterans status, national origin, disability, marital status, parental status, socioeconomic status and/or origin. Whitehead Institute is an Equal Opportunity Employer.
Company Description
WHITEHEAD INSTITUTE for BIOMEDICAL RESEARCH\r\nWhitehead Institute for Biomedical Research is a leading, nonprofit research and educational institution that has defined the cutting edge of biomedical science, creating a legacy of research excellence and academic eminence since 1982. Wholly independent in its governance, finances and research programs, Whitehead shares a teaching affiliation with Massachusetts Institute of Technology (MIT), offering the intellectual, collegial and scientific benefits of a leading research university. Whitehead’s Faculty Members and Fellows run pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics and genomics—programs with a record of success. \r\n\r\nWe offer excellent benefits including a choice of health insurance options; a generous retirement plan; comprehensive dental, disability and life insurance coverage; competitive salary, substantial vacation and holiday time; and programs for tuition reimbursement, dependent care assistance, pre-tax spending accounts, and subsidized public transportation or parking. We also offer relocation assistance.\r\n\r\nThe Whitehead Institute believes diversity, equity and inclusion (DE&I) are integral to its values and mission. As a research Institute dedicated to improving human health through biomedical science, we believe that diverse thought invokes creative inquiry, drives innovation, and fuels scientific breakthrough. We welcome all individuals of all backgrounds including race, ethnicity, gender identity and expression, sexual orientation, age, veterans status, national origin, disability, marital status, parental status, socioeconomic status and/or origin. Whitehead Institute is an Equal Opportunity Employer.