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Indicated for: Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome (as adjunctive therapy to continuous positive airway pressure), Shift Work Sleep Disorder (SWSD).
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There is no major direct pharmacokinetic interaction, but the combination warrants caution due to their opposing effects on alertness: modafinil promotes wakefulness while gabapentin can cause significant drowsiness and dizziness. As a potent inducer of liver enzymes (CYP3A4), modafinil can accelerate the metabolism of the progesterone in these contraceptives, potentially reducing their effectiveness and increasing the risk of unintended pregnancy. Modafinil Over The Counter Canada - Online Overnight Legal. Diazepam (Valium) is a benzodiazepine, a powerful central nervous system depressant used for anxiety, muscle spasms, and sedation. In susceptible individuals, especially at high doses, modafinil can induce or exacerbate psychotic symptoms like hallucinations, paranoia, and delusions, due to its dopaminergic effects.
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